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President Donald Trump on Monday signed an executive order establishing the “Genesis Mission,” a new federal initiative that directs U.S. science agencies, including the Department of Energy, to expand the use of artificial intelligence in research and development.
The White House said the effort is intended to speed scientific progress in fields such as pharmaceuticals, engineering and domestic energy production. According to Politico, part of the program’s funding is expected to come from the One Big Beautiful Bill, President Trump’s wide-ranging tax and spending package enacted earlier this year.
“From the founding of our Republic, scientific discovery and technological innovation have driven American progress and prosperity,” President Trump wrote in the order. “Today, America is in a race for global technology dominance in the development of artificial intelligence, an important frontier of scientific discovery and economic growth.”
The order instructs the Energy Department to develop a new portfolio of scientific and engineering challenges that could be improved or accelerated through the use of artificial intelligence, with a particular focus on national security and energy-related projects.
“The Genesis Mission will dramatically accelerate scientific discovery, strengthen national security, secure energy dominance, enhance workforce productivity, and multiply the return on taxpayer investment into research and development, thereby furthering America’s technological dominance and global strategic leadership,” the order stated.
Michael Kratsios, who heads the White House Office of Science and Technology Policy, described the initiative as the largest federal scientific commitment in modern memory. He told reporters the Genesis Mission marked the “largest marshaling of federal scientific resources since the Apollo program,” referring to the 1960s effort that sent American astronauts to the moon.
The directive also encourages federal agencies to share more data with academic researchers, private industry, and scientific institutions to support AI-driven innovation. The administration says greater collaboration could help ensure the United States remains competitive in a rapidly advancing global technology landscape.
Further details on the program’s structure and funding distribution are expected in the coming months.
